Use of a “Catalytic” Cosolvent, N,N-Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch |
Yang, J. C. ; Niu, D. ; Karsten, B. P. ; Lima, F. ; Buchwald, S. L. . Angew. Chem. Int. Ed. 2016, 55, 2531-2535. |
Catalytic Asymmetric Hydroamination of Unactivated Internal Olefins to Aliphatic Amines |
Yang, Y. ; Shi, S. - L. ; Niu, D. ; Liu, P. ; Buchwald, S. L. . Science 2015, 349, 62 - 66. |
Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination |
Niu, D. ; Buchwald, S. L. . J. Am. Chem. Soc. 2015, 137, 9716. |