Buchwald Research Group
Advancing organic synthesis through the development of general catalytic methods and their application to challenging chemical problems.
Research
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Bioconjugation
Pd Catalysis
Cu-H Catalysis
Cu Catalysis
Stephen L. Buchwald
Steve started his independent career in 1984 at the Massachusetts Institute of Technology. He has been the Camille Dreyfus Professor of Chemistry at MIT since 1997.
He has been honored for numerous awards including the ACS Arthur C. Cope Award (2013), BBVA Foundation Frontiers of Knowledge Award in Basic Sciences (2014) and the Wolf Prize in Chemistry (2019).
Steve has mentored many postdoctoral scholars, graduate students, undergraduates and visiting students throughout the course of his career. He is the coauthor of over 550 published papers and holds 55 issued patents.
Recent Publications
Automated Flow Synthesis of Artificial Heme Enzymes for Enantiodivergent Biocatalysis
J. Am. Chem. Soc. 2025, 147, 5, 4188-4197
Giulio Fittolani, Dennis A. Kutateladze, Andrei Loas, Stephen L. Buchwald* and Bradley L. Pentelute*
Kinetic Modeling Enables Understanding of Off-Cycle Processes in Pd-Catalyzed Amination of Five-Membered Heteroaryl Halides.
J. Am. Chem. Soc. 2024, 146, 48, 33035-33047
Elaine Reichert Raguram*, Jakob C. Dahl*, Klavs F. Jensen and Stephen L. Buchwald
Copper-Catalyzed Amination of Aryl Chlorides under Mild Reaction Conditions
J. Am. Chem. Soc. 2024, 146, 38, 25949–25955
Han-Jun Ai, Seoung-Tae Kim, Cecilia Liu, and Stephen L. Buchwald*
