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Continuous-flow synthesis of 3,3-disubstituted oxindoles by a palladium-catalyzed α-arylation/alkylation sequence

contact July 16, 2015April 21, 2025
  • ← The palladium-catalyzed trifluoromethylation of vinyl sulfonates
  • Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization →
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