Martín, Rubén
Buchwald, Stephen L

A General Method for the Direct α-Arylation of Aldehydes with Aryl Bromides and Chlorides

“,
Angew. Chem. Int. Ed.
,
2007
,
46
(
38
)
,
7236-7239
.
Abstract

A catalyst system able to efficiently perform the title reaction is described. The high level of activity achieved allows for the synthesis of highly functionalized compounds with a wide variety of substitution patterns under very mild conditions.