Noël, Timothy
Naber, John R.
Hartman, Ryan L.
McMullen, Jonathan P.
Jensen, Klavs F.
Buchwald, Stephen L.

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

“,
Chem. Sci.
,
2011
,
2
,
287-290
.
Abstract

A continuous-flow palladium-catalyzed amination reaction was made possible through efficient handling of solids via acoustic irradiation. Various diarylamines were obtained with reaction times ranging from 20 s to 10 min.