Michael Pirnot | The Buchwald Research Group

Lab Positions	Start Date	End Date	End Date2	Fellowships and Awards	Current Position	Previous Institutions
Postdoctoral Researcher	2014	2017	2017	NIH Postdoctoral Fellowship	Process Chemist at Merck	Ph.D: Princeton University, Princeton, NJ Advisor: Prof. David W. C. MacMillan Thesis: Direct b-Activation of Ketones and Aldehydes via Photoredox Organocatalysis B. Sc: University of Deleware, Newark, DE Advisor: Prof. Douglass E. Taber Thesis: Conjugate Addition of Lithiated Methylpyridines and Natural Product Synthesis

Visible Light-Mediated (Hetero)aryl Amination Using Ni(II) Salts and Photoredox Catalysis in Flow: A Synthesis of Tetracaine	Park, B. Y. ; Pirnot, M. T. ; Buchwald, S. L. . J. Org. Chem. 2020, 85, 3234-3244.
A Dual Palladium and Copper Hydride Catalyzed Approach for Alkyl–Aryl Cross-Coupling of Aryl Halides and Olefins	Friis, S. D. ; Pirnot, M. T. ; Dupuis, L. N. ; Buchwald, S. L. . Angew. Chem. Int. Ed. 2017, 56, 7242–7246 .
Asymmetric Copper Hydride-Catalyzed Markovnikov Hydrosilylation of Vinylarenes and Vinyl Heterocycles	Gribble, M. W. ; Pirnot, M. T. ; Bandar, J. S. ; Liu, R. Y. ; Buchwald, S. L. . J. Am. Chem. Soc 2017, 139, 2192-2195.
Copper Hydride-Catalyzed Hydroamination of Alkenes and Alkynes	Pirnot, M. T. ; Wang, Y. - M. ; Buchwald, S. L. . Angew. Chem. Int. Ed. 2016, 54, 2-12.
Aryl amination using ligand-free Ni(II) salts and photoredox catalysis	Corcoran, E. B. ; Pirnot, M. T. ; Lin, S. ; Dreher, S. D. ; DiRocco, D. A. ; Davies, I. W. ; Buchwald, S. L. ; MacMillan, D. W. C. . Science 2016.
Asymmetric Hydroarylation of Vinylarenes Using a Synergistic Combination of CuH and Pd Catalysis	Friis, S. D. ; Pirnot, M. T. ; Buchwald, S. L. . J. Am. Chem. Soc. 2016, 138, 8372-8375.
Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins	Bandar, J. S. ; Pirnot, M. T. ; Buchwald, S. L. . J. Am. Chem. Soc. 2015, 137, 14812-14818.

Publications