Palladium−Peptide Oxidative Addition Complexes for Bioconjugation |
Rojas, A. Jose; Wolfe, J. M. ; Dhanjee, H. H. ; Buslov, I. ; Truex, N. L. ; Liu, R. Y. ; Massefski, W. ; Pentelute, B. ; Buchwald, S. L. . Chem. Sci. 2022, 13, 11891-11895. |
The Quest for the Ideal Base: Rational Design of a Nickel Precatalyst Enables Mild, Homogeneous C–N Cross-Coupling |
Liu, R. Y. ; Dennis, J. M. ; Buchwald, S. L. . J. Am. Chem. Soc. 2020, 142, 4500 - 4507. |
CuH-Catalyzed Olefin Functionalization: From Hydroamination to Carbonyl Addition |
Liu, R. Y. ; Buchwald, S. L. . Acc. Chem. Res. 2020, 53, 1229-1243. |
Evidence for Simultaneous Dearomatization of Two Aromatic Rings Under Mild Conditions in Cu(I)-Catalyzed Direct Asymmetric Dearomatization of Pyridine |
Gribble, M. W. ; Liu, R. Y. ; Buchwald, S. L. . J. Am. Chem. Soc. 2020, 142, 11252-11269. |
Engaging Aldehydes in CuH-Catalyzed Reductive Coupling Reactions: Stereoselective Allylation with Unactivated 1,3-Diene Pronucleophiles |
Li*, C. ; Shin*, K. ; Y.Liu, R. ; Buchwald, S. L. . Angew. Chem. Int. Ed. 2019, 58, 17074-17080. |
Enantioselective Allylation Using Allene, a Petroleum Cracking Byproduct |
Liu, R. Y. ; Zhou, Y. ; Yang, Y. ; Buchwald, S. L. . J. Am. Chem. Soc. 2019, 141, 2251-2256. |
CuH-Catalyzed Enantioselective Ketone Allylation with 1,3-Dienes: Scope, Mechanism, and Applications |
Li, C. ; Liu, R. Y. ; Jesikiewicz, L. T. ; Yang, Y. ; Liu, P. ; Buchwald, S. L. . J. Am. Chem. Soc. 2019, 141, 5062-5070. |
Pd-Catalyzed C–N Coupling Reactions Facilitated by Organic Bases: Mechanistic Investigation Leads to Enhanced Reactivity in the Arylation of Weakly Binding Amines |
Dennis, J. M. ; White, N. A. ; Liu, R. Y. ; Buchwald, S. L. . ACS Catalysis 2019, 9, 3822 - 3830. |
Monophosphine Ligands Promote Pd-Catalyzed C–S Cross-Coupling Reactions at Room Temperature with Soluble Bases |
Xu, J. ; Liu, R. Y. ; Yeung, C. S. ; Buchwald, S. L. . ACS Catalysis 2019, 9, 6461 - 6466. |
CuH-Catalyzed Asymmetric Reduction of α,β-Unsaturated Carboxylic Acids to β-Chiral Aldehydes |
Zhou, Y. ; Bandar, J. S. ; Liu, R. Y. ; Buchwald, S. L. . J. Am. Chem. Soc 2018, 140, 606-609. |
Mechanistic Insight Facilitates Discovery of a Mild and Efficient Copper-Catalyzed Dehydration of Primary Amides to Nitriles Using Hydrosilanes |
Liu, R. Y. ; Bae, M. ; Buchwald, S. L. . J. Am. Chem. Soc. 2018, 140, 1627-1631. |
A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes |
Tsai, E. ; Liu, R. Y. ; Yang, Y. ; Buchwald, S. L. . J. Am. Chem. Soc 2018, 140, 2007-2011. |
Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common, Soluble Base in C–N Coupling |
Dennis, J. M. ; White, N. A. ; Liu, R. Y. ; Buchwald, S. L. . J. Am. Chem. Soc. 2018, 140, 4721–4725. |
Copper-Catalyzed Enantioselective Hydroamination of Alkenes |
Liu, R. Y. ; Buchwald, S. L. . Org. Syn. 2018, 95, 80-96. |
Asymmetric Copper Hydride-Catalyzed Markovnikov Hydrosilylation of Vinylarenes and Vinyl Heterocycles |
Gribble, M. W. ; Pirnot, M. T. ; Bandar, J. S. ; Liu, R. Y. ; Buchwald, S. L. . J. Am. Chem. Soc 2017, 139, 2192-2195. |
Ligand-Substrate Dispersion Facilitates the Copper-Catalyzed Hydroamination of Unactivated Olefins |
Lu, G. ; Liu, R. Y. ; Yang, Y. ; Fang, C. ; Lambrecht, D. S. ; Buchwald, S. L. ; Liu, P. . J. Am. Chem. Soc 2017, 139, 16548–16555. |
Regiodivergent and Diastereoselective CuH-Catalyzed Allylation of Imines with Terminal Allenes |
Liu, R. Y. ; Yang, Y. ; Buchwald, S. L. . Angew. Chem. Int. Ed. 2016, 55, 14077-14080. |