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Title Journal Year
Palladium-Catalyzed Negishi Coupling of α-CF3 Oxiranyl Zincate: Access to Chiral CF3-substituted Benzylic Tertiary Alcohols J. Am. Chem. Soc 2017
Use of a “Catalytic” Cosolvent, N,N-Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch Angew. Chem. Int. Ed. 2016
Continuous-Flow Synthesis of Biaryls by Negishi Cross-Coupling of Fluoro- and Trifluoromethyl-Substituted (Hetero)arenes Angew. Chem. Int. Ed. 2016
Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz–Schiemann Reaction Angew. Chem. Int. Ed. 2016
Suzuki-Miyaura cross-coupling optimization enabled by automated feedback Reaction Chemistry & Engineering 2016
Rapid and Efficient Copper-Catalyzed Finkelstein Reaction of (Hetero)Aromatics under Continuous-Flow Conditions Angew. Chem. Int. Ed. 2014
Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a C—N Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence Angew. Chem. Int. Ed. 2013
Rapid and Efficient Trifluoromethylation of Aromatic and Heteroaromatic Compounds Using Potassium Trifluoroacetate Enabled by a Flow System Angew. Chem. Int. Ed. 2013
Enantioselective β-arylation of ketones enabled by lithiation/borylation/1,4-addition sequence under flow conditions Angew. Chem. Int. Ed. 2012
Continuous-Flow Preparation and Use of β-Chloro Enals Using the Vilsmeier Reagent Org. Process Res. Dev. 2012
Accelerating Palladium-Catalyzed C-F Bond Formation: Use of a Microflow Packed-Bed Reactor Angew. Chem. Int. Ed. 2011
Continuous-flow synthesis of biaryls enabled by multistep solid-handling in a lithiation/borylation/Suzuki-Miyaura cross-coupling sequence Angew. Chem. Int. Ed. 2011
Use of precatalysts greatly facilitate palladium-catalyzed alkynylations in batch and continuous-flow conditions Chem. Sci. 2011
Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation Chem. Sci. 2011
Overcoming the Challenges of Solid Bridging and Constriction during Pd-Catalyzed C-N Bond Formation in Microreactors Org. Process Res. Dev. 2010
Packed-bed reactors for continuous-flow C-N cross-coupling Angew. Chem. Int. Ed. 2010