Ali, Mayssam H.
Buchwald, Stephen L.

An Improved Method for the Palladium-Catalyzed Amination of Aryl Iodides

“,
J. Org. Chem.
,
2001
,
66
(
8
)
,
2560-2565
.
Abstract

Aryl iodides are coupled with amines to give the corresponding arylamines in high yield in the presence of palladium, a suitable ligand, and NaOt-Bu. Functionalized aryl iodides give good yields of the corresponding arylamines when Cs2CO3 is substituted as the base.