Edward J. Hennessy

Edward J. Hennessy

Lab Positions	Start Date	End Date	End Date2	Degree Received	Current Position	Previous Institutions
Graduate Student		2005	2005	PhD	Associate Director Moderna Therapeutics, Cambridge, MA

Publications

Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs	Wang, H. ; Duennwald, M. L. ; Roberts, B. E. ; Rozeboom, L. M. ; Zhang, Y. L. ; Steele, A. D. ; Krishnan, R. ; Su, L. J. ; Griffin, D. ; Mukhopadhyay, S. ; Hennessy, E. J. ; Weigele, P. ; Blanchard, B. J. ; King, J. ; Deniz, A. A. ; Buchwald, S. L. ; Ingram, V. M. ; Lindquist, S. ; Shorter, J. . Proc Natl Acad Sci U S A 2008, 105, 7159-64.
Synthesis of 4,5-Dianilinophthalimide and Related Analogues for Potential Treatment of Alzheimer's Disease via Palladium-Catalyzed Amination	Hennessy, E. J. ; Buchwald, S. L. . J. Org. Chem. 2005, 70, 7371-7375.
Synthesis of Substituted Oxindoles from α-Chloroacetanilides via Palladium-Catalyzed C−H Functionalization	Hennessy, E. J. ; Buchwald, S. L. . J. Am. Chem. Soc. 2003, 125, 12084-12085.
A General and Mild Copper-Catalyzed Arylation of Diethyl Malonate	Hennessy, E. J. ; Buchwald, S. L. . Org. Lett. 2002, 4, 269-272.

Patents

Copper-catalyzed Formation of Carbon-heteroatom and Carbon-carbon bonds.	Buchwald, S. L.; Klapars, A.; Antilla, J. C.; Job, G. E.; Wolter, M.; Kwong, F. Y.; Nordmann, G.; Hennessy, E. J.	U.S. Patent No. 7,115,784	October 3, 2006
Copper-catalyzed Formation of Carbon-heteroatom and Carbon-carbon bonds.	Buchwald, S.L.; Klapars, A.; Antilla, J.C.; Job, Gabriel E.; Wolter, M.; Kwong, Fuk Y.; Nordmann, G.; Hennessy, E. J.	U.S. Patent No. 6,867,298	March 15, 2005
Copper-Catalyzed Formation of Carbon-Heteroatom and Carbon-Carbon Bonds.	Buchwald, S.L.; Klapars, A; Antilla, J.C.; Job, G.E.; Wolter, M.; Kwong, F.Y.; Nordmann, G.; Hennessy, E.J.	U.S. Patent No. 6,759,554	July 6, 2004