Convenient Method for the Preparation of Weinreb Amides via Pd-Catalyzed Aminocarbonylation of Aryl Bromides at Atmospheric Pressure

J. R. Martinelli, Freckmann, D. M. M. , and Buchwald, S. L. “Convenient Method for the Preparation of Weinreb Amides via Pd-Catalyzed Aminocarbonylation of Aryl Bromides at Atmospheric Pressure”, Org. Lett., 2006, 8(21), 4843-4846.

Abstract:

The direct transformation of aryl bromides into the corresponding Weinreb amides via Pd-catalyzed aminocarbonylation at atmospheric pressure is reported.

Authors

Joseph R. Martinelli, Dominique M. M. Freckmann