Mechanistic Studies

Papers describing mechanistic studies.

The Evolution of Pd(0)/Pd(II)-Catalyzed Aromatic Fluorination

A. C. Sather and Buchwald, S. L. “The Evolution of Pd(0)/Pd(II)-Catalyzed Aromatic Fluorination”, Acc. of Chem. Res., 2016, 49(10), 2146-2157.

Biaryl Phosphine Based Pd(II) Amido Complexes: The Effect of Ligand Structure on Reductive Elimination

P. L. Arrechea and Buchwald, S. L. “Biaryl Phosphine Based Pd(II) Amido Complexes: The Effect of Ligand Structure on Reductive Elimination”, J. Am. Chem. Soc., 2016, 138(38), 12486-12493.

Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins

J. S. Bandar, Pirnot, M. T. , and Buchwald, S. L. “Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins”, J. Am. Chem. Soc., 2015, 137(46), 14812-14818.

Electronic Dependence of C−O Reductive Elimination from Palladium (Aryl)neopentoxide Complexes

R. A. Widenhoefer and Buchwald, S. L. “Electronic Dependence of C−O Reductive Elimination from Palladium (Aryl)neopentoxide Complexes”, J. Am. Chem. Soc., 1998, 120(26), 6504-6511.

Direct observation of C-O reductive elimination from palladium aryl alkoxide complexes to form aryl ethers

R. A. Widenhoefer, Zhong, H. A. , and Buchwald, S. L. “Direct observation of C-O reductive elimination from palladium aryl alkoxide complexes to form aryl ethers”, J. Am. Chem. Soc., 1997, 119(29), 6787-6795.

An improved catalyst system for aromatic carbon-nitrogen bond formation: The possible involvement of bis(phosphine) palladium complexes as key intermediates

J. P. Wolfe, Wagaw, S. , and Buchwald, S. L. “An improved catalyst system for aromatic carbon-nitrogen bond formation: The possible involvement of bis(phosphine) palladium complexes as key intermediates”, J. Am. Chem. Soc., 1996, 118, 7215-7216.

Formation of palladium bis(amine) complexes from reaction of amine with palladium tris(o-tolyl)phosphine mono(amine) complexes

R. A. Widenhoefer and Buchwald, S. L. “Formation of palladium bis(amine) complexes from reaction of amine with palladium tris(o-tolyl)phosphine mono(amine) complexes”, Organometallics, 1996, 15(16), 3534-3542.

Halide and Amine Influence in the Equilibrium Formation of Palladium Tris(o-tolyl)phosphine Mono(amine) Complexes from Palladium Aryl Halide Dimers

R. A. Widenhoefer and Buchwald, S. L. “Halide and Amine Influence in the Equilibrium Formation of Palladium Tris(o-tolyl)phosphine Mono(amine) Complexes from Palladium Aryl Halide Dimers”, Organometallics, 1996, 15(12), 2755-2763.

Kinetics and Mechanism of the Reductive Elimination of Cyclic Titanocene Iminoacyls

J. Campora, Buchwald, S. L. , Gutierrez-Puebla, E. , and Monge, A. “Kinetics and Mechanism of the Reductive Elimination of Cyclic Titanocene Iminoacyls”, Organometallics, 1995, 14(4), 2039-2046.

Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Kinetic and Mechanistic Investigations

C. A. Willoughby and Buchwald, S. L. “Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Kinetic and Mechanistic Investigations”, J. Am. Chem. Soc., 1994, 116(26), 11703-11714.

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