C—C (All)

Carbon—carbon bond forming reactions.

CuH-Catalyzed Olefin Functionalization: From Hydroamination to Carbonyl Addition

R. Y. Liu and Buchwald, S. L. “CuH-Catalyzed Olefin Functionalization: From Hydroamination to Carbonyl Addition”, Acc. Chem. Res., 2020, 53(6), 1229-1243.

CuH-Catalyzed Regio- and Enantioselective Formal Hydroformylation of Vinyl Arenes

S. Garhwal, Dong, Y. , Mai, B. Khanh, Liu, P. , and Buchwald, S. L. “CuH-Catalyzed Regio- and Enantioselective Formal Hydroformylation of Vinyl Arenes”, J. Am. Chem. Soc., 2024, 146(20), 13733-13740.

Stereoselective Synthesis of Trisubstituted Alkenes via Copper Hydride-Catalyzed Alkyne Hydroalkylation

D. A. Kutateladze, Mai, B. Khanh, Dong, Y. , Zhang, Y. , Liu, P. , and Buchwald, S. L. “Stereoselective Synthesis of Trisubstituted Alkenes via Copper Hydride-Catalyzed Alkyne Hydroalkylation”, J. Am. Chem. Soc., 2023, 145(32), 17557-17563.

Abiotic peptides as carriers of information for the encoding of small-molecule library synthesis

S. L. Rössler, Grob, N. M. , Buchwald, S. L. , and Pentelute, B. L. “Abiotic peptides as carriers of information for the encoding of small-molecule library synthesis”, Science, 2023, 379, 939–946.

A General Strategy for the Asymmetric Preparation of α-Stereogenic Allyl Silanes, Germanes, and Boronate Esters via Dual Copper Hydride- and Palladium-Catalysis

J. Levi Knippel, Ni, A. Z. , Schuppe, A. W. , and Buchwald, S. L. “A General Strategy for the Asymmetric Preparation of α-Stereogenic Allyl Silanes, Germanes, and Boronate Esters via Dual Copper Hydride- and Palladium-Catalysis”, Angew. Chem. Int. Ed. , 2022, 61, e202212630.

Copper Hydride-Catalyzed Enantioselective Olefin Hydromethylation

Y. Dong, Shin, K. , Mai, B. Khanh, Liu, P. , and Buchwald, S. L. “Copper Hydride-Catalyzed Enantioselective Olefin Hydromethylation”, J. Am. Chem. Soc., 2022, 144(36), 16303-16309.

Confronting the Challenging Asymmetric Carbonyl 1,2-Addition Using Vinyl Heteroarene Pronucleophiles: Ligand-Controlled Regiodivergent Processes through a Dearomatized Allyl–Cu Species

Y. Dong, Schuppe, A. W. , Mai, B. Khah, Liu, P. , and Buchwald, S. L. “Confronting the Challenging Asymmetric Carbonyl 1,2-Addition Using Vinyl Heteroarene Pronucleophiles: Ligand-Controlled Regiodivergent Processes through a Dearomatized Allyl–Cu Species”, J. Am. Chem. Soc., 2022, 144(13), 5985-5995.

A Dual CuH- and Pd-Catalyzed Stereoselective Synthesis of Highly Substituted 1,3-Dienes

C. - J. Hou, Schuppe, A. W. , Knippel, J. Levi, Ni, A. Z. , and Buchwald, S. L. “A Dual CuH- and Pd-Catalyzed Stereoselective Synthesis of Highly Substituted 1,3-Dienes”, Org. Lett., 2021, 23(22), 8816-8821.

Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis

A. W. Schuppe, Knippel, J. Levi, Borrajo-Calleja, G. M. , and Buchwald, S. L. “Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis”, J. Am. Chem. Soc. , 2021, 143, 5330-5335.

CuH-Catalyzed Regio- and Enantioselective Hydrocarboxylation of Allenes; Toward Carboxylic Acids with Acyclic Quarternary Centers

S. Feng and Buchwald, S. L. “CuH-Catalyzed Regio- and Enantioselective Hydrocarboxylation of Allenes; Toward Carboxylic Acids with Acyclic Quarternary Centers”, J. Am. Chem. Soc., 2021, 143(13), 4935-4941.

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