Copper

Copper-catalyzed reactions.

Enantioselective CuH-Catalyzed Hydroallylation of Vinylarenes

Y. M. Wang and Buchwald, S. L. “Enantioselective CuH-Catalyzed Hydroallylation of Vinylarenes”, J. Am. Chem. Soc., 2016, 138, 5024-5027.

Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols

S. - L. Shi, Wong, Z. L. , and Buchwald, S. L. “Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols”, Nature, 2016, 532, 353-356.

A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination

S. Zhu, Niljianskul, N. , and Buchwald, S. L. “A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination”, Nat. Chem., 2016, 8, 144-150.

Copper Hydride-Catalyzed Hydroamination of Alkenes and Alkynes

M. T. Pirnot, Wang, Y. - M. , and Buchwald, S. L. “Copper Hydride-Catalyzed Hydroamination of Alkenes and Alkynes”, Angew. Chem. Int. Ed., 2016, 54, 2-12.

Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins

J. S. Bandar, Pirnot, M. T. , and Buchwald, S. L. “Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins”, J. Am. Chem. Soc., 2015, 137(46), 14812-14818.

Submitted.

Enantioselective Synthesis of α-Aminosilanes by Copper-Catalyzed Hydroamination of Vinylsilanes

N. Niljianskul, Zhu, S. , and Buchwald, S. L. “Enantioselective Synthesis of α-Aminosilanes by Copper-Catalyzed Hydroamination of Vinylsilanes”, Angew. Chem. Int. Ed., 2015, 54(5), 1638 - 1641.

Enantioselective Synthesis of Carbo- and Heterocycles Through a CuH-Catalyzed Hydroalkylation Approach

Y. - M. Wang, Bruno, N. C. , Placeres, Á. L. , Zhu, S. , and Buchwald, S. L. “Enantioselective Synthesis of Carbo- and Heterocycles Through a CuH-Catalyzed Hydroalkylation Approach”, J. Am. Chem. Soc., 2015, 137(33), 10524–10527.

An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides

D. T. Cohen, Zhang, C. , Pentelute, B. L. , and Buchwald, S. L. “An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides”, J. Am. Chem. Soc., 2015, 137(31), 9784.

Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination

D. Niu and Buchwald, S. L. “Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination”, J. Am. Chem. Soc., 2015, 137(30), 9716.

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